SELECTED PUBLICATIONS

Refereed Articles

1. Brading, A.F. and J.H. Widdicombe. 1974. An estimate of the sodium/potassium pump activity and the numbers of pump sites in the smooth muscle of the guinea-pig taenia coli, using [3H] ouabain. J. Physiol. 238:235-249.

2. Widdicombe, J.H. 1977. Ouabain-sensitive ion fluxes in the smooth muscle of the guinea-pig? taenia coli. J. Physiol. 266:235-254.

3. Brading, A.F. and J.H. Widdicombe. 1977. The use of lanthanum to estimate the numbers of extracellular cation-exchanging sites in the guinea-pig? taenia coli, and its effects on transmembrane monovalent ion movements. J. Physiol. 266:255-273.

4. Widdicombe, J.H., A. Johns and D.M. Paton. 1977. Responses of monkey oviduct to transmural stimulation and to drugs. J. Reprod. Fertil. 50:141-144.

5. Widdicombe, J.H. and D.M. Paton. 1979. Fine structure and innervation of smooth muscle in the monkey oviduct. Gynecol. Obstet. Invest. 10:221-230.

6. Widdicombe, J. H. and D.M. Paton. 1979. The uptake and efflux of a-aminoisobutyric acid by the smooth muscle of the guinea pig? taenia coli. Can. J. Physiol. Pharmacol. 57:1114-1121.

7. Widdicombe, J.H., I.F. Ueki, I. Bruderman and J.A. Nadel. 1979. The effects of sodium substitution and ouabain on ion transport by dog tracheal epithelium. Am. Rev. Respir. Dis. 120:385-392.

8. Widdicombe, J.H., C.B. Basbaum and J.Y. Yee. 1979. Localization of Na pumps in the tracheal epithelium of the dog. J. Cell Biol. 82:380-390.

9. Widdicombe, J.H. and A.F. Brading. 1980. A possible role of linked Na and Cl movement in active Cl uptake in smooth muscle. Pflugers Arch. 386:35-37.

10. Welsh, M.J. and J.H. Widdicombe. 1980. Pathways of ion movement in the canine tracheal epithelium. Am. J. Physiol. 239:F215-F221.

11. Welsh, M.J., J.H. Widdicombe and J. A. Nadel. 1980. Fluid transport across the canine tracheal epithelium. J. Appl. Physiol. 49:905-909.

12. Widdicombe, J.H. and M.J. Welsh. 1980. Anion selectivity of the chloride-transport process in dog tracheal epithelium. Am. J. Physiol. 239:C112-C117.

13. Widdicombe, J.H., C.B. Basbaum and E. Highland. 1981. Ion contents and other properties of isolated cells from dog tracheal epithelium. Am. J. Physiol. 241:C184-C192.

14. Mason, R.J., M.C. Williams, J.H. Widdicombe, M.J. Sanders, D.S. Misfeldt and L.C. Berry. 1982. Transepithelial transport by pulmonary alveolar type II cells in primary culture. Proc. Natl. Acad. Sci. USA. 79:6033-6037.

15. Nathanson, I., J.H. Widdicombe and P.J. Barnes. 1983. Effect of vasoactive intestinal peptide on ion transport across dog tracheal epithelium. J. Appl. Physiol. 55:1844-1848.

16. Nathanson, I.T., J.H. Widdicombe and J.A. Nadel. 1983. Effect of amphotericin B on ion and fluid movement across dog tracheal epithelium. J. Appl. Physiol. 55:1257-1261.

17. Widdicombe, J.H., I.T. Nathanson and E. Highland. 1983. Effects of "loop" diuretics on ion transport by dog tracheal epithelium. Am. J. Physiol. 245:C388-C396.

18. Basbaum, C.B., M.A. Grillo and J.H. Widdicombe. 1984. Muscarinic receptors: evidence for a nonuniform distribution in tracheal smooth muscle and exocrine glands. J. Neurosci. 4:508-520.

19. Coleman, D.L., I.K. Tuet and J.H. Widdicombe. 1984. Electrical properties of dog tracheal epithelial cells grown in monolayer culture. Am. J. Physiol. 246:C355-C359.

20. Corrales, R.J., J.A. Nadel and J.H. Widdicombe. 1984. Source of the fluid component of secretions from tracheal submucosal glands in cats. J. Appl. Physiol. 56:1076-1082.

21. Widdicombe, J.H., C.B. Basbaum and E. Highland. 1985. Sodium pump density of cells from the dog? tracheal mucosa. Am. J. Physiol. 248:C389-C398.

22. Leikauf, G.D., I.F. Ueki, J.A. Nadel and J.H. Widdicombe. 1985. Bradykinin stimulates chloride secretion and prostaglandin E2 release by canine tracheal epithelium. Am. J. Physiol. 248: F48-F55.

23. Widdicombe, J.H., D.L. Coleman, W.E. Finkbeiner and I.K. Tuet. 1985. Electrical properties of monolayers cultured from cells of human tracheal mucosa. J. Appl. Physiol. 58:1729-1735.

24. Widdicombe, J.H., M.J. Welsh and W.E. Finkbeiner. 1985. Cystic fibrosis decreases the apical membrane chloride permeability of monolayers cultured from cells of tracheal epithelium. Proc. Natl. Acad. Sci., USA. 82:6167-6171.

25. Leikauf, G.D., I.F. Ueki, J.H. Widdicombe and J.A. Nadel. 1986. Alteration of chloride secretion across canine tracheal epithelium by lipoxygenase products of arachidonic acid. Am. J. Physiol. 250:F47-F53.

26. Widdicombe, J.H., A.A. Gashi, C.B. Basbaum and I.T. Nathanson. 1986. Structural changes associated with fluid absorption by dog tracheal epithelium. Exp. Lung Research 10:57-69.

27. Corrales, R.J., D.L. Coleman, D.B. Jacoby, G.D. Leikauf, H.L. Hahn, J.A. Nadel and J.H. Widdicombe. 1986. Ion transport across tracheal epithelia of cat and ferret. J. Applied Physiol. 61:1065-1070

28. Widdicombe, J.H. 1986. Cystic fibrosis and b-adrenergic response of airway epithelial cell cultures. Am. J. Physiol. 251:R818-R822.

29. Widdicombe, J.H., D.L. Coleman, W.E. Finkbeiner and D.S. Friend. 1987. Primary cultures of the dog? tracheal epithelium: fine structure, fluid and electrolyte transport. Cell Tissue Res. 247:95-103.

30. Ferrara, N., D.K. Fuji, P.C. Goldsmith, J.H. Widdicombe and R.I. Wiener. 1987. Transport epithelial characteristics of cultured bovine pituitary follicular cells. Am. J. Physiol. 252:E304-E312.

31. Barthelson, R.A., D.B. Jacoby and J.H. Widdicombe. 1987. Regulation of chloride secretion in dog tracheal epithelium by protein kinase C. Am. J. Physiol. 253:C802-C808.

32. Barthelson, R.A. and J.H. Widdicombe. 1987. Cyclic adenosine monophosphate-dependent kinase in cystic fibrosis tracheal epithelium. J. Clin. Invest. 80:1799-1802.

33. Mrsny, R.J., G.B. Birrell, J.J. Volwerk, J.H. Widdicombe and O.H. Griffith. 1987. A new approach to the ultrastructural localization of a cell surface receptor: affinity-gold labeling of NaK-ATPase. Eur. J. Cell Biol. 45:200-208.

34. Jacoby, D.B., I.F. Ueki, J.H. Widdicombe, D.A. Loegering, G.J. Gleich and J.A. Nadel. 1988. Effects of human eosinophil major basic protein on ion transport in dog tracheal epithelium. Am. Rev. Resp. Dis. 137:13-16.

35. Tamaoki, J., I.F. Ueki, J.H. Widdicombe and J.A. Nadel. 1988. Stimulation of Cl secretion by neurokinin A and neurokinin B in canine tracheal epithelium. Am. Rev. Respir. Dis. 137:899-902 .

36. Fong, P., N.P. Illsley, J.H. Widdicombe and A.S. Verkman. 1988. Chloride transport in apical membrane vesicles from bovine tracheal epithelium: characterization using a fluorescent indicator. J. Memb. Biol. 104:233-239.

37. Verkman A.S., R. Takla, B. Sefton, C.B. Basbaum and J.H. Widdicombe. 1989. Quantitative fluorescence measurement of chloride transport mechanisms in phospholipid vesicles. Biochem. J. 28:4240-4244.

38. Widdicombe, J.H., I.F. Ueki, D. Emery, D. Margolskee, J. Yergey and J.A. Nadel. 1989. Release of cyclooxygenase products from primary cultures of tracheal epithelia of dog and human. Am. J. Physiol. 257:L361-L365.

39. Chao, A.C., J.H. Widdicombe and A.S. Verkman. 1990. Chloride conductive and cotransport mechanisms in cultures of canine tracheal epithelial cells measured by an entrapped fluorescent indicator. J. Memb. Biol. 113:193-202.

40. Gruenert, D.C., C.B. Basbaum and J.H. Widdicombe. 1990. Long-term culture of normal and cystic fibrosis epithelial cells grown under serum-free conditions. In Vitro. 26:411-418.

41. Chapman, D.C., J.H. Widdicombe and R.D. Bland. 1990. Developmental differences in rabbit lung epithelial Na+ -K+ -ATPase. Am. J. Physiol. 259:L481-L487.

42. Shen, B-Q., C-M Yang and J.H. Widdicombe. 1991. A rapid procedure for obtaining tracheal apical membranes. Am. J. Physiol. 261:L102-L105

43. Kondo, M., W.E. Finkbeiner and J.H. Widdicombe, 1991. A simple technique for culture of highly differentiated cells from dog tracheal epithelium. Am. J. Physiol. 261:L106-L117

44. Fong, P., A.C. Chao and J.H. Widdicombe 1991. Potassium dependence of Na-Cl cotransport in dog tracheal epithelium. Am. J. Physiol. 261:L290-L295

45. Katayama, Y. and J.H. Widdicombe 1991. Halide transport in Xenopus oocytes. J. Physiol. 443:587-599.

46. Yamaya, M., W.E. Finkbeiner and J.H. Widdicombe 1991. Ion transport by cultures of human tracheobronchial submucosal glands. Am. J. Physiol. 261:261:L485-L490.

47. Yamaya, M., W.E. Finkbeiner and J.H. Widdicombe 1991. Altered ion transport by tracheal glands in cystic fibrosis. Am. J. Physiol. 261:L491-L494.

48. Hartmann, T., M. Kondo, H. Mochizuki, A.S. Verkman and J.H. Widdicombe. 1992. Calcium-dependent regulation of Cl secretion in tracheal epithelium. Am. J. Physiol. 262:L163-L168.

49. Kondo, M., W.E. Finkbeiner and J.H. Widdicombe. 1992. Changes in permeability of dog tracheal epithelium in response to hydrostatic pressure. Am. J. Physiol. 262:L176-L182.

50. Mochizuki, H., A.C. Chao and J.H. Widdicombe. 1992. Arachidonic acid inhibits Cl secretion in cultures of dog tracheal epithelium. Life Sci. 50:1129-1135.

51. Finkbeiner, W.E., J.H. Widdicombe, L. Hu and C.B. Basbaum. 1992. Bovine tracheal serous cell secretion: Role of cAMP and cAMP-dependent protein kinase. Am. J. Physiol. 262:L574-L581.

52. Yamaya, M., W.E. Finkbeiner, S.Y Chun and J.H. Widdicombe. 1992. Differentiated structure and function of cultures from human tracheal epithelium. Am J. Physiol. 262:L713-L724.

53. Kondo, M., W.E. Finkbeiner and J.H. Widdicombe. 1993. Cultures of cow tracheal epithelium with differentiated ultrastructure and ion transport. In Vitro. 29A:19-24.

54. Yamaya, M., T. Ohrui, W.E. Finkbeiner and J.H. Widdicombe. 1993. Calcium-dependent Cl secretion across cultures of tracheal surface epithelium and glands. Am. J. Physiol. 265:L170-LL177.

55. Shen, B-Q., R. A. Barthelson, W. Skach, D. C. Gruenert, E. Sigal, R. J. Mrsny, and J. H. Widdicombe. 1993. Mechanism of inhibition of cAMP-dependent epithelial chloride secretion by phorbol esters. J. Biol. Chem. 268: 19070-19075.

56. Jiang, C., W. E. Finkbeiner, J. H. Widdicombe, P. B. McCray, and S. S. Miller. 1993. Altered fluid transport across airway epithelium in cystic fibrosis. Science. 262: 424-427.

57. Cozens, A., M. Yezzi, K. Kunzelmann, T. Ohrui, L. Chin, K. Eng, W. E. Finkbeiner, J. H. Widdicombe, and D. C. Gruenert. 1994. CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am. J. Resp. Cell Mol. Biol. 10:38-47.

58. Shen, B-Q., W. E. Finkbeiner, J. J. Wine, R. J. Mrsny, and J. H. Widdicombe. 1994. Calu-3: A human airway epithelial cell line which shows cAMP-dependent Cl secretion. Am. J. Physiol. 266:L493-L501

59. Haws, C., W. E. Finkbeiner, J. H. Widdicombe, and J. J. Wine. 1994. CFTR in CaLu-3 human airway cells: channel properties and role in cAMP-activated Cl- conductance. Am. J. Physiol. 266:L502-L513.

60. Ohrui, T., W. Skach, M. Thompson, J. Matsumoto-Pon, C. Calayag, and J. H. Widdicombe. 1994. Radiotracer studies of CFTR expressed in Xenopus oocytes. Am. J. Physiol. 266:C1586-C1593

61. Finkbeiner, W. E., B-Q. Shen, and J. H. Widdicombe. 1994. Chloride secretion and function of serous and mucous cells of human airway glands. Am. J. Physiol. 267:L206-L210

62. Finkbeiner, W. E. and J. H. Widdicombe. 1994. Serial propagation of cells from human tracheobronchial glands. In Vitro 30A:817-818

63. Ohrui, T., Shen, B-Q., R. J. Mrsny, and J. H. Widdicombe. 1995. A method for measuring Cl efflux from dispersed cells of airway epithelium. J. Applied Physiol. 78:1197-1202.

64. Ilek, B., H. Fischer, G. F. Santos, J. H. Widdicombe, T. E. Machen, and W. W. Reenstra. 1995. cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein. Am. J. Physiol. 268:C886-C893.

65. Shen, B-Q., J. H. Widdicombe, and R. J. Mrsny. 1995. Effects of lovastatin on trafficking of cystic fibrosis transmembrane conductance regulator in human tracheal epithelium. J. Biol. Chem. 270:25102-25106.

66. Shen, B-Q., W. E. Finkbeiner, R. J. Mrsny, and J. H. Widdicombe. 1995. Role of CFTR in Cl secretion across human tracheal epithelium. Am. J. Physiol. 269:L561-L566.

67. Sawa, T. H. Miyazaki, J-F. Pittet, J.H. Widdicombe, M.A. Gropper, S. Hashimoto, D.J. Conrad, H.G. Folkesson, R. Debs, J.R. Forsayeth, B. Fox, and J.P. Wiener-Kronish. 1996. Intraluminal water increases expression of plasmid DNA in rat lung. Hum. Gene Ther. 7:933-941.

68. Widdicombe, J. H., F. Azizi, T. Kang, and J.F. Pittet. 1996. Transient permeabilization of airway epithelium by mucosal water. J. Applied Physiol. 81:491-499.

69. Wu, D. X-Y., C. Y. C. Lee, J. H. Widdicombe, and S. J. Bastacky. 1996. Ultrastructure of tracheal surface liquid: low-temperature scanning electron microscopy. Scanning 18:589-592

70. Azizi, F., P. S. Matsumoto, D. X-Y. Wu, and J. H. Widdicombe. 1997. Effects of hydrostatic pressure on permeability of airway epithelium. Exp. Lung Res. 23:257-267.

71. Shen, B-Q., R. J. Panos, K. Hansen-Guzman, J. H. Widdicombe, and R. J. Mrsny. 1997. Hepatocyte growth factor stimulates the differentiation of human tracheal epithelium in vitro. Am. J. Physiol. 272:L1115-L1120.

72. Jiang, C., W. E. Finkbeiner, J. H. Widdicombe, and S. S. Miller. 1997. Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis. J. Physiol. 501:647-658.

73. Xiong, X., A. Bragin, J. H. Widdicombe, J. Cohn, and W. R. Skach. 1997. Structural cues involved in endoplasmic reticulum degradation of G95E and G91R mutant cystic fibrosis transmembrane conductance regulator. J. Clin. Invest. 100: 1079-1088

74. Lee, C. Y., J. Matsumoto-Pon, and J. H. Widdicombe. 1997. Cultured lung epithelium: a cellular model for lung preservation. Cryobiology 35: 209-218

75. Wu, D. X-Y., C. Y. C. Lee, S. N. Uyekubo, H. K. Choi, S. J. Bastacky, and J. H. Widdicombe. 1998. Regulation of the depth of surface liquid in bovine trachea. Am. J. Physiol. 274:L388-L395

76. Lee, M. C. , C. M. Penland, J. H. Widdicombe, and J. J. Wine. 1998. Evidence that Calu-3 human airway cells secrete bicarbonate. Am. J. Physiol. 274:L450-L453

77. Zhang, L., D. Wang, H. Fischer, P-D. Fan, J. H. Widdicombe, Y. W. Kan, and J-Y. Dong. 1998. Efficient expression of CFTR function with adeno-associated virus vectors that carry shortened CFTR genes. Proc. Natl. Acad. Sci. USA 95:10158-10163

78. Zabner, J., J. J. Smith, P. H. Karp, J. H. Widdicombe, and M. J. Welsh. 1998. Loss of CFTR chloride channels decreases salt absorption by cystic fibrosis airway epithelia. Mol. Cell 2:397-403.

79. Evans, D. J., P. S. Matsumoto, J. H. Widdicombe, C. Li-Yun, A. A. Maminishkis, and S. S. Miller. 1998. Pseudomonas aeruginosa induces changes in fluid transport across airway epithelia. Am. J. Physiol. 275:C1284-C1290

80. Uyekubo, S. N., H. Fischer, A. Maminishkis, B. Illek, S. S. Miller, and J. H. Widdicombe. 1998. Cyclic AMP-dependent absorption of chloride across airway epithelium. Am. J. Physiol 275:L1219-L1227.

REVIEWS, BOOKS AND BOOK CHAPTERS

1. Brading, A.F. and J.H. Widdicombe. 1976. Interaction between sodium and calcium movements in smooth muscle. Les Colloques de LՉNSERM, vol 50: Smooth Muscle Pharmacology and Physiology. Editions INSERM, Paris, 35-245.

2. Paton, D.M., J.H. Widdicombe, D.E. Rheaume and A. Johns. 1978. The role of the adrenergic innervation of the oviduct in the regulation of mammalian ovum transport. Pharm. Rev. 29:67-102.

3. Widdicombe, J.H. and M.J. Welsh. 1980. Ion transport by dog tracheal epithelium. Fed. Proc. 39:3062-3066.

4. Widdicombe, J.H. 1981. The ionic properties of the sodium pump in smooth muscle. Smooth Muscle: An Assessment of Recent Knowledge. Edward Arnold, London, 93-104.

5. Mason, R.J., M.C. Williams and J.H. Widdicombe. 1982. Secretion and fluid transport by alveolar type II cells. Chest 81:61S-63S.

6. Mason, R.J., M.C. Williams and J.H. Widdicombe. 1983. Fluid and electrolyte balance across monolayers of alveolar type II cells in vitro. Am. Rev. Resp. Dis. 127:S24-S28.

7. Basbaum, C.B., P.J. Barnes, M.A. Grillo, J.H. Widdicombe and J.A. Nadel. 1983. Adrenergic and cholinergic receptors in submocosal glands of ferret trachea: autoradiographic localization. Eur. J. Respir. Dis. 64 [Suppl. 128]:433-435.

8. Widdicombe, J.H. 1984. Fluid transport across airway epithelia. Mucus and Mucosa. Pitman Books Ltd, London (Ciba Found. Symp. 109), 109-120.

9. Nadel, J.A., D.B. Borson, C.B. Basbaum and J.H. Widdicombe. 1984. Techniques for studying airway mucus secretion, ion transport and water movement. Techniques in the Life Sciences. Techniques in Respiratory Physiology - Part I. Elsevier Scientific Publishers Ireland Ltd., County Clare, Ireland, 1-35.

10. Mason, R.J., M.C. Williams and J.H. Widdicombe. 1984. Cell culture systems for studying RDS. Respiratory Distress Syndrome. Academic Press, London, 87-96.

11. Nadel, J.A., J.H. Widdicombe, and A.C. Peatfield. 1985. Regulation of airway secretions, ion transport and water movement. Handbook of Physiology, Section 3: The Respiratory System, Volume I. Circulation and Nonrespiratory Functions. The American Physiological Society, Bethesda MD, 419-445.

12. Welsh, M.J. and J.H. Widdicombe. 1985. Research on cystic fibrosis: step 3?. J. Appl. Physiol. 58: 1999-2001.

13. Widdicombe J.H. (guest editor). 1986. The Upper Airways (Clin. Chest Med. vol. 7, no. 2). W. B. Saunders Company, Philadelphia.

14. Widdicombe, J.H. 1986. Ion transport by tracheal epithelial cells in culture. Clin. Chest Med. 7:299-305.

15. Davis, B., J.H. Widdicombe and C.B. Basbaum. 1987. Control of normal and abnormal secretion in airways. Bronchial Hyperresponsiveness. Blackwell Scientific Publications Ltd., Oxford.

16. Widdicombe, J.H. 1987. Altered chloride transport of tracheal epithelium in cystic fibrosis. Prog. Clin. Biol. Res. 254:115-126.

17. Drazen, J.M., H.A. Boushey, S.T. Holgate, M. Kaliner, P. OՂyrne, M. Valentine, J.H. Widdicombe and A. Woolcock. 1987. The pathogenesis of severe asthmaЁ consensus report from the workshop on pathogenesis. J. Allergy Clin. Immunol. 80:428-437.

18. Widdicombe, J.H. 1987. Fluid transport by airway epithelia. Biorheology. 24:551-555.

19. Widdicombe J.H. and R.A. Barthelson. 1988. Altered chloride transport across primary cultures of tracheal epithelium in cystic fibrosis. The Cellular and Molecular Basis of Cystic Fibrosis. San Francisco Press, San Francisco. pp. 377-382.

20. Widdicombe, J.H. 1988. Culture of tracheal epithelial cells. Methods in Bronchial Mucology. Raven Press, New York. pp. 291-302.

21. Widdicombe, J.H. 1988. Electrical methods for studying ion and fluid transport across airway epithelia. Methods in Bronchial Mucology. Raven Press, New York. pp. 335-345.

22. Widdicombe, J.H. 1988. Asthma - What are the important experiments? 3. Epithelial Function. Am. Rev. Resp. Dis. 138:731-732.

23. Widdicombe, J.H., 1989. Airway diseases: role of epithelium and inflammatory peptides. Am. J. Physiol. 257:L144-L146.

24. Widdicombe, J.H. 1990. Use of airway epithelial cell cultures in studies of ion transport. Am. J. Physiol. 258:L13-L18.

25. Widdicombe, J.H. 1990. Role of the epithelium in airway hyperreactivity. Jap. J. Thor. Dis. 28:1272-1274.

26. Widdicombe, J.H. 1991. Ion transport by airway epithelia. In: The Lung, Scientific Foundations, edited by Crystal, R.G. and J.B. West. Raven Press, N. Y. pp 263-271.

27. Widdicombe, J.H. 1991. The Physiology of the Airway Epithelium. In: The Airway Epithelium: Structure and Function in Health and Disease. Edited by S.E. Farmer and D.W.P. Hay, Marcel Dekker, N. Y.

28. Wine, J.J., D.J. Brayden, G. Hagiwara, M.E. Krouse, T.C. Law, U.J. Muller, C.K. Solc, C.L. Ward, J.H. Widdicombe and Y. Xia. 1991. Cystic fibrosis, the CFTR and rectifying Cl- channels. Adv. Exp. Biol. Med. 290:253-272.

29. Widdicombe, J.H., M. Kondo and H. Mochizuki. 1991. Regulation of airway mucosal ion transport. Int. Arch. Allergy Appl. Immunol. 94:56-61.

30. Widdicombe, J.H. and J.J. Wine. 1991. The basic defect in cystic fibrosis. Trends Biochem. Sci. 16:474-477.

31. Finkbeiner, W.E. and J.H. Widdicombe. 1992. Control of nasal and airway secretions, ion transport, and water movement. In: A Comprehensive Treatise on Pulmonary Toxicology. Volume 1. Comparative Biology of the Normal Lung, Edited by R. Parent. CRC Press. Boca Raton, Florida. pp 633-657.

32. Dodge, J.A., D.J.H. Brock and J.H. Widdicombe. (eds.) 1993. Cystic Fibrosis - Current Topics. Vol 1. John Wiley & Sons, Chichester.

33. Widdicombe, J. H., M. Yamaya, and W. E. Finkbeiner. 1993. Ion transport by cultures of human submucosal gland cells. Ped. Pulm. (Suppl. 9). 143-144.

34. Widdicombe, J. H. 1994. Structure, growth and repair of epithelia. Chapter 1 in: Handbook of Immunopharmacology: Immunopharmacology of epithelial barriers. Edited by R. Goldie. Academic Press, London. pp. 1-17.

35. Widdicombe, J. H. 1994. Epithelial cells in controlling airway lining fluid. Chapter 43 in: Asthma and Rhinitis, Edited by W. Busse and S. Holgate. Blackwell Scientific Publications, Cambridge, MA. pp. 565-572.

36. Widdicombe, J. H. 1994. Ion and fluid transport by airway epithelium. Chapter 10 in: Airway Secretion: Physiological Bases for the Control of Mucus Hypersecretion. Edited by T. Takishima and S. Shimura, Marcel Dekker, N. Y. pp. 399-431.

37. Widdicombe, J. H., B-Q. Shen, and W. E. Finkbeiner. 1994. Structure and function of human airway mucous glands in health and disease. Adv. Struct. Biol. 3:225-241.

38. Wine, J. J., W. E.Finkbeiner, C. Haws, M. E. Krouse, S. Moon, J. H. Widdicombe and Y. Xia. 1994. CFTR and other Cl- channels in human airway cells. Jap. J. Physiol. 44 (suppl 2):S199-S205.

39. Widdicombe, J. H., S. S. Miller, C. Jiang and W. E. Finkbeiner. 1994. Defective function of airway serous gland cells in cystic fibrosis. Ped. Pulm. (Suppl. 10). 146-147.

40. Dodge, J. A., D. J. H. Brock, and J. H. Widdicombe (Eds.). 1994. Cystic Fibrosis - Current Topics. Vol. 2. John Wiley & Sons. Chichester.

41. Widdicombe, J. H., S. S. Miller and W. E. Finkbeiner. 1994. Altered regulation of airway fluid content. In: Cystic Fibrosis - Current Topics. Vol. 2. Edited by J. A. Dodge, D. J. H. Brock and J. H. Widdicombe. John Wiley & Sons. Chichester. pp. 109-129.

42. Widdicombe, J. H. 1994. Accumulation of airway mucus in cystic fibrosis. Pulm. Pharmacol. 7:225-233.

43. Widdicombe, J. H., and J. G. Widdicombe. 1995. Regulation of human airway surface liquid. Resp. Physiol. 99:3-12.

44. Gruenert, D. C., W. E. Finkbeiner, and J. H. Widdicombe. 1995. Culture and transformation of human airway epithelial cells. Am. J. Physiol. 268:L347-L360.

46. Widdicombe, J. H., 1995. Role of serous cells in pathogenesis of CF. Ped. Pulm. (Suppl. 12). 69-70.

47. Widdicombe, J. H. 1996. Ion transport by airway epithelia. Chapter 39 in: The Lung, Scientific Foundations, Vol. 2 edited by R. G. Crystal, J. B. West, E. R. Weibel, and P. J. Barnes. Raven Press, N. Y. pp 39.1-39.12.

48. Dodge, J. A., D. J. H. Brock, and J. H. Widdicombe (Eds.). 1996. Cystic Fibrosis - Current Topics. Vol. 3. John Wiley & Sons. Chichester.

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